In this randomized controlled trial of IV alteplase for ischemic stroke, researchers evaluated CT or brain MRI scans before treatment and 24 to 48 hours after treatment for acute lesion visibility, extent, and swelling.
Article Correctness Is Author's Responsibility: Vagus Nerve Stimulation Superior to Sham Device for Acute Migraine Treatment
Researchers sought to determine whether noninvasive vagus nerve stimulation significantly reduces the amount of pain or even takes pain away entirely in patients with episodic migraine.
Article Correctness Is Author's Responsibility: Cognitive Decline Worsens With Memantine, ChEIs in Patients With Alzheimer’s
The concomitant use of cholinesterase inhibitors or memantine was associated with an increased rate of cognitive decline in clinical trials of patients with Alzheimer disease.
Article Correctness Is Author's Responsibility: Bafiertam Gets Tentative Approval for Relapsing Multiple Sclerosis
Bafiertam is a new fumarate bioequialent alternative to its prodrug, Tecfidera (dimethyl fumarate; Biogen).
Article Correctness Is Author's Responsibility: Relapsing MS: Greater Treatment Satisfaction Following Switch to Teriflunomide
Investigators reviewed patient-reported outcomes to assess treatment satisfaction with teriflunomide and also looked at feedback from physicians regarding the effectiveness of teriflunomide when used in routine clinical practice.
Article Correctness Is Author's Responsibility: Race May Affect Phenotype, Age of Onset, and Severity of Neuromyelitis Optica Spectrum Disorder
Investigators analyzed racial differences in the clinical features of neuromyelitis optica spectrum disorder.
Article Correctness Is Author's Responsibility: Hospital Infections Increase 30-Day Readmission Rates in Patients With Stroke
Investigators examined the effect of common infections such as urinary tract infections, sepsis, and pneumonia on >300,000 patients with ischemic stroke.
Article Correctness Is Author's Responsibility: Infratentorial Lesions Beneficial for Differentiating Fabry Disease vs MS
Investigators sought to determine whether absence of lesions in 2 specific brain regions can distinguish Fabry disease from multiple sclerosis.
Article Correctness Is Author's Responsibility: Very Early Mobilization After Stroke Does Not Improve Survival Over Usual Care
Investigators examined whether very early mobilization, started ?48 hours after onset of stroke symptoms, improves recovery and survival after stroke compared with more delayed mobilization.
Article Correctness Is Author's Responsibility: Migraine With Aura Increases Risk for Carotid Thickening in Middle-Aged Women
Migraine with aura increased the risk for diffuse carotid thickening and migraine without aura was associated with a low risk for carotid plaques and arterial stiffening in middle-aged women.